The vasodilatory mechanism of tadalafil was investigated.
Dose size was measured after administration using duplex ultrasound.
Full response was found in the pro-bono treatment group versus no improvement on all 7 measures.
In the placebo-controlled group, sedation was achieved in 8 of the 9 female mice, whereas no improvement was observed on blood pressure measurements.
Blood flow in the pro-bono group was increased with treatment during the course of 16, 48, and 67 hours, respectively.
No improvements were noted on blood flow measurements other than increase in clitoral pain.